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Supermicro SYS-421GU-TNXR GPU server
Supermicro · GPU SuperServer

SYS-421GU-TNXR

DP Intel 4U Universal GPU System with NVIDIA HGX™ H200 4-GPU.

Sold and configured by Semifly — an authorized Supermicro reseller.
4U
Form factor
4
GPUs
Intel Xeon
2× socket
6 bays
Drive bays
Air
Cooling
4×3000W
Power

Key Applications

  • AI / Deep Learning Training
  • Large Language Models (LLMs)
  • Generative AI & Inference
  • High-Performance Computing (HPC)

Key Features

  • Supports up to 4 GPUs — NVIDIA® Hopper
  • NVIDIA SXM: HGX H200 4-GPU (141GB), HGX H100 4-GPU (80GB)
  • 2× socket — 5th Gen Intel® Xeon®/4th Gen Intel® Xeon® Scalable processors
  • Storage: 6 default drive bays
  • Power: 4x 3000W Redundant

Official Supermicro specifications for the SYS-421GU-TNXR.

Motherboard

ModelSuper X13DGU

Processor

CPUDual Socket E (LGA-4677)
5th Gen Intel® Xeon® / 4th Gen Intel® Xeon® Scalable processors
Core CountUp to 56C/112T; Up to 112.5MB Cache per CPU

GPU

Max GPU Count4 onboard GPUs
Supported GPUNVIDIA SXM: HGX H200 4-GPU (141GB), HGX H100 4-GPU (80GB)
CPU-GPU InterconnectPCIe 5.0 x16 CPU-to-GPU Interconnect
GPU-GPU InterconnectNVIDIA® NVLink™

System Memory

MemorySlot Count: 32 DIMM slots
Max Memory (2DPC): Up to 8TB 5600MT/s ECC DDR5

On-Board Devices

Network Connectivity2 RJ45 10GbE with Intel® X710-AT2
NetworkingFlexible networking (AIOM) options

Input / Output

Video1 VGA port

System BIOS

BIOS TypeAMI 32MB SPI Flash EEPROM

Management

SoftwareSuperCloud Composer®; Supermicro Server Manager (SSM); Supermicro Update Manager (SUM); SuperDoctor® 5 (SD5); Super Diagnostics Offline (SDO); Thin-Agent Service (TAS); SuperServer Automation Assistant (SAA)

PC Health Monitoring

CPU8+4 Phase-switching voltage regulator; monitors CPU Cores, Chipset & Memory voltages
FANFans with tachometer monitoring; PWM fan connectors with speed control
TemperatureMonitoring for CPU and chassis environment; thermal control for fan connectors

Chassis

Form Factor4U Rackmount
ModelCSE-458GTS-R3K06P

Dimensions and Weight

Enclosure449 x 175.6 x 833 mm (17.67" x 7" x 32.79")
Package700 x 370 x 1260 mm (27.55" x 14.57" x 49.6")
WeightGross Weight: 140 lbs (64 kg)
Net Weight: 105 lbs (48 kg)
Available ColorBlack front & silver body

Expansion Slots

PCI-Express (PCIe) ConfigurationDefault: 8 PCIe 5.0 x16 LP slots

Drive Bays / Storage

Drive Bays ConfigurationDefault: Total 6 bays — 6 front hot-swap 2.5" NVMe/SATA
M.22 M.2 NVMe/SATA slots (M-key)

System Cooling

FansUp to 5 heavy duty fans with optimal fan speed control
Air Shroud1 Air Shroud
Liquid CoolingDirect-to-Chip (D2C) Cold Plate (optional)

Operating Environment

Environmental Spec.Operating Temperature: 10°C to 35°C (50°F to 95°F)
Non-operating Temperature: -40°C to 60°C (-40°F to 140°F)
Operating Relative Humidity: 8% to 90% (non-condensing)
Non-operating Relative Humidity: 5% to 95% (non-condensing)

Power Supply

PSU4x 3000W Redundant Titanium Level (96%)

Official Supermicro firmware, drivers, manuals, and certification resources for the SYS-421GU-TNXR. Semifly does not host these files — each link opens Supermicro's official page so you always get the latest version.

BIOS Downloads

Latest system BIOS. Flash only if you have a BIOS-related issue.

Supermicro

BMC Firmware Downloads

Latest BMC firmware for out-of-band management.

Supermicro

Drivers & Utilities

Select your OS and device type on Supermicro's download center.

Supermicro

User's Manuals

Official user's manual (HTML / PDF).

Supermicro

Datasheet (PDF)

Official one-page datasheet for the SYS-421GU-TNXR.

Supermicro

OS Compatibility & Certification

Certified operating systems and compatibility matrix.

Supermicro

Free Remote Testing (JumpStart)

Validate and benchmark your workload on this platform remotely.

Supermicro

Need a specific revision, a quote, or help selecting GPUs, CPUs, drives and networking? Talk to Semifly →

Built to orderWe configure GPUs, CPUs, memory, drives, and networking to your exact AI/HPC workload.
Validated & burn-in testedEvery system is assembled, firmware-matched, and stress-tested before it ships.
Lifecycle supportAuthorized Supermicro reseller — warranty, RMA, and deployment help included.

Configure the SYS-421GU-TNXR

Tell us your GPU model and count, CPU, memory, drives, and networking targets — we'll return a build-to-order quote, typically within one business day.

Request a Quote →
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Supermicro®, SuperServer®, and related product names and images are trademarks or registered trademarks of Super Micro Computer, Inc. Semifly is an authorized Supermicro reseller. Specifications are provided by the manufacturer and subject to change.